Effect of endometrial thickness changes on clinical pregnancy rates after progesterone administration in a single frozen-thawed euploid blastocyst transfer cycle using natural cycles with luteal support for PGT-SR- and PGT-M-assisted reproduction: a retrospective cohort study

Table 4 Association between endometrial thickness change ratio and clinical pregnancy rate in different models — by using data after multiple imputation

	Crude model^a		Adjusted model I^b		Adjusted model II^c
	OR (95% CI)	P value	OR (95% CI)	P value	OR (95% CI)	P value
Endometrial thickness change ratio (per 10%)	1.24 (1.02, 1.52)	0.034	1.24 (1.01, 1.53)	0.041	1.25 (1.02, 1.54)	0.036
Grouping of endometrial thickness
= 0 (non-change)	Reference		Reference		Reference
< 0 (compaction)	0.48 (0.23,0.99)	0.046	0.47 (0.23,0.99)	0.047	0.44 (0.21,0.93)	0.032
> 0 (expansion)	1.08 (0.56,2.06)	0.826	1.04 (0.54,2.02)	0.899	1.03 (0.53,2.01)	0.935
P for trend	0.025		0.028		0.018

Note BMI body mass index, AMH anti-Müllerian hormone, E2 estradiol, P progesterone, OR odds ratio, CI confidence interval.
^aNo adjustments for other covariates
^bAdjusted for female age at transfer, BMI, infertility duration and infertility type
^cAdjusted for all covariables in model I plus AMH, E2 on the day of P administration and genetic category

ISSN: 1477-7827