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Fig. 1 | Reproductive Biology and Endocrinology

Fig. 1

From: Circ_0043532 regulates miR-182/SGK3 axis to promote granulosa cell progression in polycystic ovary syndrome

Fig. 1

Circ_0043532 knockdown hampered cell proliferation and cell cycle process and facilitated cell apoptosis in PCOS GCs and KGN cells. (A) The expression of circ_0043532 in PCOS GCs and non-PCOS GCs was measured by qRT-PCR. (B) The expression of circ_0043532 in IOSE80 cells and KGN cells was measured by qRT-PCR analysis. (C-H) PCOS GCs and KGN cells were transfected with si-con or si-circ_0043532. (C) QRT-PCR assay was conducted for circ_0043532 and TOP2A expression in PCOS GCs and KGN cells. (D and E) The proliferation of PCOS GCs and KGN cells was determined via EdU assay and MTT assay. (F-H) Cell cycle and cell apoptosis in PCOS GCs and KGN cells were analyzed by flow cytometry analysis. (I and J) The protein level of BAX in PCOS GCs and KGN cells was measured via western blot assay. *P < 0.05

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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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