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Table 2 Differential metabolites in FF samples between DOR and NOR groups

From: UHPLC-MS-MS analysis of oxylipins metabolomics components of follicular fluid in infertile individuals with diminished ovarian reserve

Metabolites

VIP

P-value

Fold change

Type

±20-HDoHE

1.46468

0.00481

0.68185

Down

±5-iso PGF2α-VI

1.05784

0.01656

0.55571

Down

12S-HHTrE

1.76019

0.00415

0.52086

Down

15-deoxy-Δ12,14-PGJ2

1.27131

0.03509

0.63420

Down

1a,1b-dihomo PGE2

2.48940

0.01361

0.28674

Down

1a,1b-dihomo PGF2α

1.82901

0.02880

0.53937

Down

20-COOH-AA

1.75008

0.00401

0.67958

Down

20-HETE

1.11775

0.02031

0.29838

Down

8S,15S-DiHETE

1.38584

0.00450

0.70519

Down

PGA2

2.32409

0.01828

0.13424

Down

PGD2

1.08593

0.04879

0.36052

Down

PGE1

2.01038

0.00705

0.41340

Down

PGF1α

1.33950

0.04522

0.54329

Down

PGF2α

2.18401

0.01426

0.34922

Down

PGJ2

1.66952

0.03160

0.24083

Down

  1. FF follicular fluid, DOR diminished ovarian reserve, NOR normal ovarian reserve, VIP variable importance in the projection