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Table 2 Summary of results of meta-analyses of comparison between sequential transfer and cleavage embryo transfer

From: Sequential cleavage and blastocyst embryo transfer and IVF outcomes: a systematic review

Outcome indicator

Studies

Samples

Heterogeneity

Effect model

RR (95%CI)

P value

Chemical pregnancy

3

423

P=0.73 I2=0%

Fixed

1.59 (1.21-2.09)

<0.01*

Clinical pregnancy

10

2474

P=0.19 I2=28%

Fixed

1.42(1.26-1.60)

<0.01*

RIF

6

1440

P=0.03 I2=59%

Random

1.58 (1.17–2.13)

<0.01*

NRIF

4

1034

P=0.97 I2=0%

Random

1.44 (1.20–1.66)

<0.01*

Embryo implantation

4

3206

P<0.01 I2=89%

Random

1.67 (0.89–3.14)

0.11

Clinical miscarriage

5

517

P=0.19 I2=35%

Fixed

0.83(0.57-1.22)

0.35

RIF

3

315

P=0.39 I2=0%

Fixed

1.12 (0.71–1.77)

0.62

NRIF

2

202

P=0.34 I2=0%

Fixed

0.50 (0.25–1.02)

0.06

Multiple pregnancy

8

642

P=0.25 I2=23%

Fixed

1.10(0.83-1.47)

0.05

RIF

6

440

P=0.43 I2=0%

Fixed

1.47 (1.01–2.16)

0.05

NRIF

2

202

P=0.19 I2=35%

Fixed

0.72 ( 0.45–1.14)

0.16

Live birth

2

531

P=0.91 I2=0%

Fixed

1.99 (1.47–2.71)

<0.01*

  1. Abbreviations: NRIF Non-RIF;*P<0.01