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Fig. 3 | Reproductive Biology and Endocrinology

Fig. 3

From: TRIB3 regulates FSHR expression in human granulosa cells under high levels of free fatty acids

Fig. 3

hGCs treated with PA in vitro. A Western blot analysis with tubulin used as the loading control. B PA increased TRIB3 levels in a concentration-dependent manner. C PA decreased FSHR levels in a concentration-dependent manner. D,E Reduced p-Akt and increased p-GSK3β protein levels indicating the Akt/GSK3β signaling was aberrantly activated in hGCs treated with PA. *P < 0.05

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