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Fig. 7 | Reproductive Biology and Endocrinology

Fig. 7

From: Irisin alleviates obesity-related spermatogenesis dysfunction via the regulation of the AMPKα signalling pathway

Fig. 7

The protective effects of irisin on spermatogenesis function were abolished after AMPK knockout. A-B Sperm viability and sperm motility of the indicated groups (n = 6). C-E T level and mRNA expression of P450scc and P450c17 (n = 6). F ROS production of the indicated groups (n = 6). G Nrf2 expression in mice testes (n = 6). H-I mRNA levels of HO-1 and NQO-1 in mouse testes (n = 6). J CHOP expression in mice testes (n = 6). K Testicular Caspase-3 activity of the indicated groups (n = 6). Data are presented as the mean ± SEM. *P < 0.05 vs. the matched control

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