Fig. 1From: Irisin alleviates obesity-related spermatogenesis dysfunction via the regulation of the AMPKα signalling pathwayIrisin expression is downregulated by obesity. A The serum irisin levels of obese and control humans (Con: n = 10; Obesity: n = 9). B Correlation between sperm count and plasma irisin level (Con: n = 10; Obesity: n = 9). C Correlation between progressive sperm rate and plasma irisin level (Con: n = 10; Obesity: n = 9). D Serum irisin level of HFD mice and ND mice (n = 6). E FNDC5 expression in the testes of HFD mice and ND mice (n = 6). Data are presented as the mean ± SEM. *P < 0.05 vs. the matched controlBack to article page