Table 2 List of diseases that show interference by the DEGs and genes from the five networks

DEGs in ectopic to control

 Developmental

19

44.19

2.14E-11

 Metabolic

17

39.53

0.038479

 Neurological

12

27.91

0.024028

 Cleft lip/Cleft palate

8

18.60

1.21E-05

 Bone mineral density

7

16.28

1.64E-04

 Vision

7

16.28

0.002492

 Parkinson's disease

4

9.30

0.003099

 Colobomatous microphthalmia

3

6.98

1.86E-04

 Clubfoot

3

6.98

0.001869

 Obstructive sleep apnea

3

6.98

0.00642

 Hirschsprung's disease

2

4.65

0.034825

DEGs in eutopic to control

 Developmental

16

43.24

8.90E-09

 Neurological

10

27.03

0.084075

 Psychological

9

24.32

0.027439

 Cleft lip/Cleft palate

6

16.22

8.20E-04

 Parkinson's disease

5

13.51

1.46E-04

 Autism

5

13.51

0.004516

 Bone mineral density

5

13.51

0.007412

 Vision

5

13.51

0.041046

Genes in network A

 Metabolic

13

46.43

0.03939

 Developmental

12

42.86

1.51E-06

 Psychological

11

39.29

1.60E-04

 Autism

6

21.43

1.30E-04

 Cleft lip/Cleft palate

6

21.43

2.09E-04

 Bone mineral density

6

21.43

2.51E-04

 Parkinson's disease

5

17.86

4.70E-05

 Talipes equinovarus

2

7.14

0.005847

 Neurodevelopmental psychiatric disorders

2

7.14

0.007304

 SIDS/sudden infant death syndrome

2

7.14

0.038844

Genes in network B

 Cleft lip/Cleft palate

3

25

0.012792

 Cleft lip with and without cleft palate

2

16.67

0.013342

 Bone mineral density

3

25

0.013805

 Developmental

4

33.33

0.023658

 Sleep apnea, obstructive

2

16.67

0.026536

Genes in network C

 Developmental

7

46.67

1.47E-04

 Clubfoot

3

20

1.97E-04

 Bone mineral density

4

26.67

0.002301

 Metabolic

9

60

0.004216