Fig. 2

A Venn diagram for DEGs (P < 0.05). DEGs in the ectopic samples compared to normal samples (black ellipse), eutopic samples in comparison to normal samples (green ellipse), and ectopic samples compared to eutopic samples (red ellipse). Genes that were significantly upregulated are enclosed in black, green and red rectangles according to the above mentioned legend. In the multi-colored rectangles, each color represents upregulation in the relevant analysis in the corresponding agreement. B Heat map for all genes. Right column is logFC of ectopic samples compared to normal samples and the left column is the logFC of eutopic samples in comparison to normal samples. logFC: Logarithm fold change; UP: Significant upregulation; Down: Significant downregulation; None: Non-significant changes. C,D PCA analysis of gene expression in the nine sample groups. Triangle, circle, and square represent normal endometrial tissues of the control women, and ectopic endometrial tissues and eutopic endometrial tissues from patients, respectively. C: PCA of DEGs. D: PCA of non-DEGs