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Table 1 Baseline characteristics of women at first IVF cycle treated with either GnRH-agonist or GnRH-antagonist protocol and after PSM

From: Cumulative live birth rates between GnRH-agonist long and GnRH-antagonist protocol in one ART cycle when all embryos transferred: real-word data of 18,853 women from China

 

Unmatch / Matched

GnRH-a (Unmatch n = 16,827;

Matched n = 1704)

GnRH-ant (Unmatch n = 2026;

Matched n = 1735)

P

Age at oocytes retrieval (years)

U

30.88 ± 4.05(30.81–31.07)

34.33 ± 5.71(33.95–34.61)

 < 0.001

M

34.10 ± 4.11(34.07–34.57)

34.02 ± 5.64(33.56–34.23)

0.392

Duration of infertility (years)

U

4.9 ± 3.53(4.84–4.98)

5.73 ± 4.56(5.38–5.88)

 < 0.001

M

5.83 ± 4.41(5.51–6.04)

5.70 ± 4.49(5.29–5.81)

0.233

BMI (kg/m2)

U

21.94 ± 2.81(21.93–22.06)

22.37 ± 2.76(22.25–22.56)

 < 0.001

M

22.38 ± 2.81(22.27–22.61)

22.28 ± 2.75(22.17–22.49)

0.601

AMH (ng/mL)

U

3.72 ± 2.81(3.70–3.81)

3.34 ± 2.26(3.31–3.92)

 < 0.001

M

3.55 ± 3.23(3.36–3.80)

3.45 ± 3.29(3.38–4.04)

0.481

FSH (mIU/mL)

U

5.5 ± 3.36(5.40–5.54)

7.08 ± 4.88(5.90–8.20)

 < 0.001

M

5.72 ± 1.69(5.53–5.73)

7.08 ± 4.09(5.84–8.32)

0.013

Gn days

U

10.78 ± 1.45(10.77–10.83)

9.72 ± 1.66(9.71–9.90)

 < 0.001

M

10.14 ± 1.61(10.05–10.22)

9.89 ± 1.58(9.85–10.03)

 < 0.001

Gn dose (mg)

U

2433.67 ± 824.98(2398.80–2489.95)

2255.09 ± 767.56(2246.95–2277.30)

 < 0.001

M

2490.99 ± 785.37(2481.58–2574.43)

2468.88 ± 844.48(2402.04–2499.23)

0.614

Retrieval oocytes

U

12.94 ± 6.33(12.90–13.15)

9.19 ± 7.23(9.03–9.82)

 < 0.001

M

10.43 ± 6.28(10.17–10.92)

9.68 ± 7.11(9.37–10.09)

 < 0.001

Available embryo

U

4.62 ± 2.82(4.52–4.63)

3.66 ± 2.78(3.44–3.75)

 < 0.001

M

3.92 ± 2.69(3.75–4.09)

3.68 ± 2.76(3.52–3.85)

 < 0.001

Cause of infertility

 Primary infertility

U

7497/16827(44.55%)

735/2026(36.28%)

 < 0.001

M

601/1704(35.27%)

641/1735(36.95%)

0.320

 Secondary infertility

U

9333/16827(55.46%)

1291/2026(63.72%)

 

M

1103/1704(64.73%)

1094/1735(63.05%)

 

IVF/ICSI

 IVF

U

13,462/16708(80.57%)

1648/1974(83.48%)

0.002

M

1398/1704(82.04%)

1433/1735(82.59%)

0.688

 ICSI

U

3246/16708(19.43%)

326/1974(16.52%)

 

M

306/1704(17.96%)

302/1735(17.41%)