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Fig. 5 | Reproductive Biology and Endocrinology

Fig. 5

From: Recombinant human IL-37 inhibited endometriosis development in a mouse model through increasing Th1/Th2 ratio by inducing the maturation of dendritic cells

Fig. 5

IL-4 mediated the promotion of EMs-DCs to Th2 differentiation. (A) Control-DCs were treated with rhIL-37, and then the production of IL-4 was examined using ELISA. N = 3. **P < 0.01 compared with Control. (B-D) The percentages of Th1 and Th2 cells, and the ratio of Th1/Th2 cells in CD4+T cells was analyzed by flow cytometry; (E) the expression levels of IFN-γ mRNA, TNF-α mRNA, IL-4 mRNA, and IL-13 mRNA in CD4+T cells were measured by qRT-PCR. N = 3. ##P < 0.01 compared with CD4+T + Control-DCs + rhIL-37 + IL-4

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