Table 3 Ang expression in Control, ARB and ± AT1KO groups

Plasma Ang

Control

ARB

AT1-KO

AngI

W2 (ng/ml)

5.12 ± 0.60

5.16 ± 0.43

5.77 ± 1.33

W4 (ng/ml)

4.16 ± .68

5.00 ± 0.91

4.39 ± 0.53

AngII

W2 (ng/ml)

5.24 ± 2.28

5.71 ± 2.12

4.17 ± 1.27

W4 (ng/ml)

5.53 ± 1.16

5.25 ± 1.73

4.59 ± 1.22

AngIII

W2 (ng/ml)

650.72 ± 91.08

599.56 ± 10.15

607.00 ± 48.35

W4 (ng/ml)

617.09 ± 58.25

617.21 ± 71.54

624.93 ± 45.33

AngIV

W2 (ng/ml)

21.07 ± 8.75

36.64 ± 11.09

30.08 ± 59.49

W4 (ng/ml)

28.15 ± 6.65

38.00 ± 13.75

25.83 ± 19.70

Total Ang mRNA

Control

ARB

AT1-KO

Testis

W2 (△Ct)

4.43 ± 1.02

5.39 ± 0.65

5.35 ± 2.07

W4 (△Ct)

6.25 ± 3.55

5.75 ± 0.50

4.77 ± 1.47

Pituitary

W2 (△Ct)

2.48 ± 0.44

1.83 ± 1.41

2.96 ± 0.73

W4 (△Ct)

2.86 ± 1.69

1.94 ± 0.81

2.1 ± 0.18

Hypothalamus

W2 (△Ct)

0.83 ± 0.53

1.91 ± 0.54

1.98 ± 1.17

W4 (△Ct)

1.75 ± 0.52

1.25 ± 1.21

2.31 ± 1.05