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Table 2 The mRNA expression of AT1 in the testis, pituitary and hypothalamus of mice in Control, ARB and ± AT1KO groups

From: Decreased angiotensin receptor 1 expression in ± AT1 Knockout mice testis results in male infertility and GnRH reduction

AT1

 

Control

ARB

 ± AT1KO

Testis

W2 (△Ct)

10.24 ± 0.29

10.29 ± 0.16

7.91 ± 1.07**

W4 (△Ct)

10.85 ± 3.09

10.53 ± 0.50

5.60 ± 1.75**

Pituitary

W2 (△Ct)

14.94 ± 0.21

14.08 ± 1.10

7.36 ± 0.69**

W4 (△Ct)

14.61 ± 1.72

14.81 ± 1.41

7.72 ± 0.10**

Hypothalamus

W2 (△Ct)

14.02 ± 1.58

14.53 ± 1.11

7.47 ± 0.94**

W4 (△Ct)

13.27 ± 0.48

13.02 ± 1.00

7.86 ± 1.15**

  1. **P < 0.01 compared to control or ARB groups
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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