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Table 1 Results of GSEA based on the differential expression analysis of RL95-2 cells treated with JAr EVs

From: Trophoblast derived extracellular vesicles specifically alter the transcriptome of endometrial cells and may constitute a critical component of embryo-maternal communication

Reactome ID Description NES FDR
R-HSA-372790 Signalling by G-protein coupled receptor (GPCR) 1.267 0.010
R-HSA-388396 GPCR downstream signalling 1.289 0.010
R-HSA-1474228 Degradation of the extracellular matrix (ECM) 1.479 0.010
R-HSA-1474244 Extracellular matrix organization 1.448 0.010
R-HSA-1474290 Collagen formation 1.490 0.010
R-HSA-216083 Integrin cell surface interactions 1.549 0.010
R-HSA-3000171 Non-integrin membrane-ECM interactions 1.456 0.011
R-HSA-3000157 Laminin interactions 1.568 0.019
R-HSA-3000178 ECM proteoglycans 1.441 0.051
  1. Results of GSEA based on the differential expression analysis of RL95-2 cells supplemented with EVs compared to non-supplemented control group RL95-2 cells. Normalized Enrichment Score (NES) and False Discovery Rate (FDR) are presented