The effects of Vitamin D3 supplementation on Spermatogram and endocrine factors in asthenozoospermia infertile men: a randomized, triple blind, placebo-controlled clinical trial

Table 3 Between group comparison of comparison of sperm parameters pre and post intervention

Variables	Time	Vitamin D3 (n = 43)	Placebo (n = 43)	P value (between)
Volume (ml)	Baseline	3.75 ± 1.49	4.13 ± 1.86	0.296^a
	12 weeks	3.84 ± 1.24	4.07 ± 1.63	0.265^b
	Change	−0.09 ± 0.42	−0.05 ± 0.34	0.076^c
P value (within)^d		0.162	0.272
Sperm count (˟ 10⁶)	Baseline	64.11 ± 10.63	65.60 ± 11.66	0.538^a
	12 weeks	66.04 ± 10.96	65.20 ± 10.65	0.721^b
	Change	1.93 ± 6.27	−0.39 ± 5.95	0.081^c
P value (within)^d		0.051	0.664
Motile sperm (%)	Baseline	33.65 ± 7.99	34.30 ± 6.22	0.675^a
	12 weeks	38.72 ± 8.42	32.86 ± 7.86	0.800^b
	Change	5.06 ± 5.77	−1.44 ± 7.87	< 0.001^c
P value (within)^d		< 0.001	0.236
Progressive sperm (%)	Baseline	18.56 ± 6.41	19.06 ± 4.89	0.685^a
	12 weeks	23.41 ± 8.62	18.18 ± 5.88	0.955^b
	Change	8.84 ± 5.89	−0.86 ± 3.51	< 0.001^c
P value (within)^d		< 0.001	0.142
Normal morphology (%)	Baseline	7.53 ± 2.98	8.20 ± 2.79	0.283^a
	12 weeks	7.79 ± 2.57	8.04 ± 2.34	0.288^b
	Change	0.25 ± 1.27	−0.16 ± 1.02	0.097^c
P value (within)^d		0.195	0.302

- Values are reported as mean ± standard deviation or Frequency and percent
- Between groups differences pre intervention, the p value are reported using the independent sample t test (a)
- Between groups differences post intervention; the p value is reported using the analysis of covariance (ANCOVA) (b)
- Between groups comparing the changes of variables, the p value is reported using the independent sample t test (c)
- Within group differences, the p value is reported using the paired t test (d)
-P < 0.05 was considered significant

ISSN: 1477-7827