Fig. 3

Histological aspects of the gerbil female and male ventral prostates from different experimental groups stained with H&E and Periodic acid and Schiff (E and F inset). a and b- Prostate from the Co group showing a normal morphologic pattern of the gland. c and d- Castrated gland from the Ca group with intense regression, observed by the decrease in lumens area and the epithelium tortuosity e and f- P3d group showed expressive histological alterations, note the cribriform architecture throughout the gland, in details inset note the microacini formed with secretion. g and h- CaP3 group recovery of atrophic effects of castration, as acini more voluminous and rounded, epithelium healthier, sml more organized compared with the castrated animals. i and j- The morphological atypia in the epithelium were substantially reduced when compared with P3, observe epithelial cells debris into the lumen and the inset details in j a epithelial cell show a clear halo around the pyknotic nucleus. k and l- CaP30 group presents recovery of atrophic effects of castration