Fig. 1
From: Downregulation of decidual SKP2 is associated with human recurrent miscarriage
SKP2 expression is downregulated in decidual tissues of women with RM. A The SKP2 mRNA levels in decidual tissues of RM patients (n = 20) and HCs (n = 20) were determined by qPCR. The relative amount of RNA was calculated using the 2-∆∆Ct method and normalized with an internal control, ACTB. B The SKP2 protein levels relative to beta-actin were determined by western blot analysis (n = 11 for each group). The results are presented as the mean ± SEM. *p < 0.05. **p < 0.01. ***p < 0.001. C Localization of SKP2 in human decidual tissues. (a) Decidual sections from the HC group; (b) Decidual sections from the RM group; (c) Negative control. Brown staining represents the target protein. HC, healthy control; RM, recurrent miscarriage. Arrowheads indicate the decidual stromal cells. Scale bars = 50 μm