Fig. 2

Venn diagram and heatmap of cumulus cells and oocytes between LPA-treated and control groups. A) VENN diagrams of differentially expressed genes between control and O-10 µM groups and C-10 µM and control groups. Control group is the group without LPA treatment. O-10 µM group is the group of oocytes treated with LPA at a concentration of 10 µM. C-10 µM group is the group of cumulus cells treated with LPA at a concentration of 10 µM. B) Heatmap of differentially expressed genes between C-Control group vs. C-10 µM, in which A-0-C-11, A-0-C-12 and A-0-C-13 were cumulus cells without LPA and A-10-C-11, A-10-C-12 and A-10-C-13 were cumulus cells treated with 10 µM of LPA. C Heatmap of differentially expressed genes between O-Control group vs. O-10 µM, in which A-0-O-11, A-0-O-12 and A-0-O-13 were oocytes without LPA and A-10-O-11, A-10-O-12 and A-10-O-13 were oocytes treated with 10 µM of LPA. LPA, Lysophosphatidic acid