Fig. 5
From: HSF1 promotes endometriosis development and glycolysis by up-regulating PFKFB3 expression
KRIBB11 plays a therapeutic role in a mouse model of endometriosis. (A) Endometriosis model was established using 5-week-old BALB/c female mice. (B) Mice were sacrificed, the endometriosis tissues and the weight of mice were analyzed (*P < 0.05). (C) The size of the ectopic tissues was observed and heterotopic tissues were weighed (*P < 0.05). (D) Immunohistochemical staining was performed to determine the HSF1 expression in the control group and the experimental group (Scale bars, 50 μm). Quantitative analyses of HSF1 expression was performed. (E) HSF1 promoted glycolysis by up-regulating the expression of PFKFB3, which induced the development of endometriosis