Skip to main content

Table 1 Baseline characteristics of the unweighted population of patients included in the analysis

From: Comparative effectiveness of recombinant human follicle-stimulating hormone alfa (r-hFSH-alfa) versus highly purified urinary human menopausal gonadotropin (hMG HP) in assisted reproductive technology (ART) treatments: a non-interventional study in Germany

 

r-hFSH-alfa

N = 17,725

hMG HP

N = 10,916

Difference

(95% CI)

Age (years) at index date, mean (SD)

33.5 (4.4)

35.6 (4.9)

2.07 (1.95, 2.18)

 n (%) with non-missing data

17,725 (100)

10,916 (100)

BMI (kg/m2) at index date, mean (SD)

23.6 (4.4)

23.7 (4.4)

0.16 (0.06, 0.27)

 n (%) with non-missing data

17,376 (98.0)

10,691 (97.9)

Type of infertility, n (%)

 Male factor

10,046 (57.7)

5545 (51.8)

−5.89 (−7.09, −4.70)

 Endometriosis

948 (5.4)

635 (5.9)

0.49 (− 0.07, 1.05)

 Hyperandrogenism/PCOS

463 (2.7)

245 (2.3)

−0.37 (− 0.74, 0.00)

 Idiopathic

1448 (8.3)

1068 (10.0)

1.66 (0.96, 2.36)

 Other

1317 (7.6)

871 (8.1)

0.57 (−0.08, 1.22)

 Pathological cycle, other endocrine disordera

650 (3.7)

417 (3.9)

0.16 (−0.30, 0.62)

 Psychological factors

7 (0.0)

5 (0.1)

0.01 (−0.04, 0.06)

 Status post sterilisation

21 (0.1)

56 (0.5)

0.40 (0.26, 0.55)

 Tubal pathology

2410 (13.8)

1804 (16.9)

3.01 (2.14, 3.89)

 Uterine, cervical factor

109 (0.6)

63 (0.6)

−0.04 (−0.22, 0.15)

Year of first stimulation cycle, n (%)

 2007

4696 (26.5)

2688 (24.6)

−1.87 (− 2.91, −0.83)

 2008

4002 (22.6)

2612 (23.9)

1.35 (0.34, 2.36)

 2009

4571 (25.8)

2879 (26.4)

0.59 (−0.46, 1.63)

 2010

4455 (25.1)

2736 (25.1)

−0.07 (−1.10, 0.96)

  1. BMI body mass index, CI confidence interval, PCOS polycystic ovary syndrome, SD standard deviation
  2. aExcluding hyperandrogenism and polycystic ovary syndrome