Comparing prediction of ongoing pregnancy and live birth outcomes in patients with advanced and younger maternal age patients using KIDScore™ day 5: a large-cohort retrospective study with single vitrified-warmed blastocyst transfer

Table 2 Embryo characteristics for each maternal age group

		< 35	35–37	38–40	41–42	≥ 43	Total
tPNf (hour)		22.8 ± 0.17	22.8 ± 0.16	22.7 ± 0.12	22.7 ± 0.13	22.5 ± 0.12	22.7 ± 0.06
t2 (hour)		25.4 ± 0.18	25.4 ± 0.16	25.2 ± 0.13	25.2 ± 0.13	25.1 ± 0.12	25.2 ± 0.06
t3 (hour)		35.4 ± 0.24	35.7 ± 0.22	35.4 ± 0.18	35.6 ± 0.19	35.4 ± 0.16	35.5 ± 0.09
t4 (hour)		37.0 ± 0.27	37.2 ± 0.23	37.0 ± 0.19	36.9 ± 0.21	37.0 ± 0.18	37.0 ± 0.09
t5 (hour)		48.2 ± 0.42	48.3 ± 0.36	48.3 ± 0.29	48.3 ± 0.32	48.4 ± 0.27	48.3 ± 0.14
tB (hour)		104.7 ± 0.61 ^a	105.6 ± 0.52 ^ab	106.2 ± 0.42 ^b	106.9 ± 0.47 ^b	108.9 ± 0.40 ^c	106.8 ± 0.21
Day of cryopreservation (%)	Day 5*	76.7	73.3	71.8	70.0	60.1	69.0
	Day 6*	22.6	25.2	27.1	28.4	37.8	29.5
	Day 7*	0.7	1.5	1.1	1.6	2.1	1.5
ICM grade (%)	A*	58.9	53.3	53.5	50.6	40.3	49.8
	B	24.3	25.4	25.9	28.6	26.7	26.4
	C*	16.8	21.2	20.6	20.8	33.3	23.8
TE grade (%)	A*	55.8	46.2	44.2	39.2	28.3	40.5
	B	20.9	24.2	26.3	25.7	22.7	24.2
	C*	23.3	29.6	29.5	35.1	49.0	35.3
KIDScore	Average	6.68 ± 2.33 ^a	6.35 ± 2.47 ^ab	6.23 ± 2.40 ^bc	6.02 ± 2.39 ^cd	5.28 ± 2.33 ^e	6.0 ± 2.4
	MAX	9.8	9.8	9.8	9.8	9.8	9.8
	75%	8.6	8.6	8.4	8.1	7.3	8.2
	Median	7.4	6.9	6.7	6.4	5.1	6.3
	25%	2.9	2.6	2.6	2.6	2.4	3.7
	MIN	1.7	1.4	1.4	1.5	1.3	1.3

Value are mean ± SEM or %
Different subscripts are statistically significant different across the maternal age groups (P < 0.05)
* An asterisk means significant correlation between the rates of each grade and maternal age groups by Cochran-Armitage trend test (P < 0.05). Timing of pronuclear fading = tPNf); Timing of 2-cell division = t2; Timing of 3-cell division = t3; Timing of 4-cell division = t4; Timing of 5-cell division = t5; Timing of blastocyst formation = tB; SEM Standard error of the means, ICM Inner cell mass, TE Trophectoderm

ISSN: 1477-7827