Table 1 Patient characteristics in women with PCOS before and after metformin treatment

Age (years)

25

31

32

BMI (kg/m²)

25.8

25.1

27.2

25.0

26.3

27.1

LH (mIU/ml)

9.9

10.13

8.19

3.06

7.50

2.51

FSH (mIU/ml)

5.12

6.25

4.73

4.48

5.62

5.52

Free testosterone (pg/ml)

1.6

1.4

2.4

0.8

1.0

0.6

DHEA-S (μg/ml)

128

287

109

129

157

–

Estradiol (pg/ml)

45

46

42

33

41

44

HOMA-IR

1.97

0.97

2.48

1.6

1.72

1.67

Endometrial classification

proliferative phase

proliferative phase

proliferative phase

secretory phase

proliferative phase

proliferative phase

Pregnancy outcome

unknown

conception after 8 months from the beginning of metformin treatment

conception after 17 months from the beginning of metformin treatment