Fig. 2

Metformin treatment changes expression of AR and HOXA10 in endometrium tissues from women with PCOS. Representative images of immunohistochemical expression of AR and HOXA10 in the endometrial tissues obtained from three women with PCOS (cases 1, 2, and 3) before and after 3 months of metformin treatment. On the left, the images show AR expression before (a, e, i) and after metformin treatment (b, f, j). On the right, the images show HOXA10 expression before (c, g, k) and after metformin treatment (d, h, l). Scale bar = 50 μM. HOXA10, homeobox A10; PCOS, polycystic ovary syndrome; AR, androgen receptor. G, glandular epithelium; S, stroma