Analysis of in vitro fertilization/intracytoplasmic sperm injection outcomes in infertile women with a history of thyroid cancer: a retrospective study

Table 2 In vitro fertilization and embryo transfer data between the TC and control groups

Characteristics	TC group (N = 64)	Control group (N = 320)	P value
Gonadotropin dose, median (IQR), IU	2175 (1500–2925)	2175 (1575–2850)	0.794
LH on hCG trigger day, median (IQR), mIU/ml	1.4 (0.8–3.1)	1.3 (0.7–2.8)	0.601
Estradiol on hCG trigger day, median (IQR), mIU/ml	5446 (3466–12,204)	6969.5 (4363.8–12,281.3)	0.121
Progesterone on hCG trigger day, median (IQR), pmol/L	2.1 (1.5–3.1)	2.3 (1.6–3.1)	0.458
No. of retrieved oocytes per cycle, median (IQR)	9 (6–14)	12 (8–17)	0.025*
Fertilization, no. (%)
IVF	36 (56.3)	223 (69.7)	0.036*
ICSI	28 (43.8)	97 (30.3)	0.036*
High-quality embryos, median (IQR)^a	3 (2–5.8)	4.5 (2–8)	0.046*
No. of embryos transferred, No. (%)
1	15 (23.4)	52 (16.3)	0.212
2	48 (75.0)	267 (83.4)
3	1 (1.6)	1 (0.3)

Abbreviations: IQR interquartile range, GnRH gonadotropin-releasing hormone, HCG human chorionic gonadotropin, ICSI intracytoplasmic sperm injection, IVF in vitro fertilization
* P < 0.05
^a Embryos were evaluated on the third day after fertilization. Good-quality embryos all developed from two pronuclei zygotes and met the following criteria: (1) had > 5 blastomeres; (2) the size difference was < 20%; and (3) fragmentation was < 50%

ISSN: 1477-7827