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Table 3 Cut-off, PPV and NPV for AMH values (ng/ml), based on Bayesian approach and PSI method with 95% CI

From: Age-specific cut-off levels of anti-Müllerian hormone can be used as diagnostic markers for polycystic ovary syndrome

  Age categorya Estimated cutoff PPV NPV
Bayesian method 20 to < 27 5.70 (5.48, 6.19) 0.98 (0.96,0.99) 0.40 (0.30,0.51)
27 to < 35 4.55 (4.52,4.64) 0.96 (0.91,0.99) 0.82 (0.78,0.86)
35 to 40 3.72 (3.55,3.80) 0.86 (0.80,0.94) 0.96 (0.93,0.98)
Total 4.54 (4.18, 5.12) 0.93 (0.89, 0.99) 0.83 (0.79, 0.87)
PSI method 20 to < 27 8.51 (7.12, 9.38) 0.85 (0.81, 0.89) 0.48 (0.25,0.72)
27 to < 35 2.91 (2.11, 3.72) 0.65 (0.61,0.69) 0.92 (0.89,0.95)
35 to 40 1.88 (1.25, 2.21) 0.57 (0.57,0.61) 0.94 (0.91,0.97)
0.83 (0.79,0.86)
Total 4.60 (4.13, 5.54) 0.93 (0.89,0.96)
  1. Note: PPV Positive predictive value, NPV Negative predictive value, PSI predictive summary index, CI confidence interval
  2. aAge categories were determined using the generalized additive models (GAMs)