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Table 3 Cut-off, PPV and NPV for AMH values (ng/ml), based on Bayesian approach and PSI method with 95% CI

From: Age-specific cut-off levels of anti-Müllerian hormone can be used as diagnostic markers for polycystic ovary syndrome

 

Age categorya

Estimated cutoff

PPV

NPV

Bayesian method

20 to < 27

5.70 (5.48, 6.19)

0.98 (0.96,0.99)

0.40 (0.30,0.51)

27 to < 35

4.55 (4.52,4.64)

0.96 (0.91,0.99)

0.82 (0.78,0.86)

35 to 40

3.72 (3.55,3.80)

0.86 (0.80,0.94)

0.96 (0.93,0.98)

Total

4.54 (4.18, 5.12)

0.93 (0.89, 0.99)

0.83 (0.79, 0.87)

PSI method

20 to < 27

8.51 (7.12, 9.38)

0.85 (0.81, 0.89)

0.48 (0.25,0.72)

27 to < 35

2.91 (2.11, 3.72)

0.65 (0.61,0.69)

0.92 (0.89,0.95)

35 to 40

1.88 (1.25, 2.21)

0.57 (0.57,0.61)

0.94 (0.91,0.97)

0.83 (0.79,0.86)

Total

4.60 (4.13, 5.54)

0.93 (0.89,0.96)

  1. Note: PPV Positive predictive value, NPV Negative predictive value, PSI predictive summary index, CI confidence interval
  2. aAge categories were determined using the generalized additive models (GAMs)