Correlation between steroid levels in follicular fluid and hormone synthesis related substances in its exosomes and embryo quality in patients with polycystic ovary syndrome

Table 1 Comparison of the clinical characteristics, endocrinological variables of PCOS patients and controls

	Control (n = 10)	PCOS (n = 10)	P value
Age (year)	30.60 ± 1.06	30.40 ± 1.09	NS
BMI (kg/m²)	20.73 ± 0.95	20.84 ± 0.94	NS
Basal serum LH (mIU/mL)	5.40 ± 0.65	6.37 ± 1.14	NS
Basal serum FSH (mIU/mL)	7.56 ± 0.89	7.14 ± 0.59	NS
Basal serum E2 (pmol/mL)	451.99 ± 316.91	708.7 ± 363.77	NS
Basal serum T (ng/ mL)	0.54 ± 0.09	1.20 ± 0.13	0.001
Basal serum P (nmol/L)	0.63 ± 0.12	0.75 ± 0.12	NS
Number of oocytes retrieved	11.1 ± 1.36	19.2 ± 1.98	0.003
MII oocytes (%)	89.1 ± 1.99	72.4 ± 16.39	0.022
Rate of fertilization (%)	77.3 ± 3.92	69.9 ± 6.50	NS
Top-quality embryo (%)	63.5 ± 5.71	33.3 ± 2.88	0.001
Rate of embryos develop to blastocyst (%)	76.7 ± 8.51	23.1 ± 7.08	0.001

Abbreviations: BMI Body mass index, FF Follicular fluid, FSH Follicle stimulating hormone, LH Luteinizing hormone, E2 Estradiol, T Testosterone, PROG Progesterone, Ret. oocyte Number of oocytes retrieved, MII oocytes Number of metaphase II oocytes, NS Not significant. Data are expressed as mean ± SEM. Differences between groups were considered significant for p ≤ 0.05

ISSN: 1477-7827