Fig. 2

Differences in complement protein levels between pre-HDP and normal pregnancy (n = 48). a, Eight differentially expressed complement proteins in the second validation set. The number after each bar represents log2 (fold change), and the bar colour represents the size of the P-value. b, Pearson’s correlation revealed the correlation of eight complement proteins and four clinical factors. The lighter colour represents the size of the correlation coefficient, and the triangle means the P-value> 0.05. SBP = systolic blood pressure, DBP = diastolic blood pressure, HGB = haemoglobin. c, PPI network of complement-related proteins. The orange nodes represent the eight complement proteins that were screened. d, Protein levels are heterogeneous between pre-GH and pre-PE