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Table 1 Demographic and main treatment characteristics for women with singleton live births according to endometrial thickness

From: Thin endometrium is associated with the risk of hypertensive disorders of pregnancy in fresh IVF/ICSI embryo transfer cycles: a retrospective cohort study of 9,266 singleton births

Characteristics

EMT ≤ 8 mm

8 < EMT ≤ 12 mm

EMT > 12 mm

P value

 

(n = 544)

(n = 6234)

(n = 2488)

 

Age (y)abc

32.39 ± 4.43

30.91 ± 4.30

30.46 ± 4.33

< 0.001e

BMI (kg/m2)

23.55 ± 3.36

23.50 ± 3.55

23.69 ± 3.65

NSe

Parity, n (%) ab

< 0.001f

 First

362 (66.5)

4800 (77.0)

1912 (76.8)

 

 High order

182 (33.5)

1434 (23.0)

576 (23.2)

 

 Primary infertility, n (%) abc

167 (30.7)

2982 (47.8)

1340 (53.9)

< 0.001f

Cause of infertility, n (%) abc

< 0.001f

 Oviduct factors

241 (44.3)

1844 (29.6)

668 (26.8)

 

 Male factor

128 (23.5)

1749 (28.1)

745 (29.9)

 

 Ovulation problems

20 (3.7)

321 (5.1)

120 (4.8)

 

 Multiple causes

43 (7.9)

896 (14.4)

364 (14.6)

 

 Unexplained

67 (12.3)

872 (14.0)

351 (14.1)

 

 Other

45 (8.3)

552 (8.9)

240 (9.6)

 

Type of ART treatment, n (%)

NSf

 IVF

396 (72.8)

4476 (71.9)

1755 (70.5)

 

 ICSI

148 (27.2)

1758 (28.2)

733 (29.5)

 

Ovarian stimulation protocol, n (%) c

< 0.001f

 GnRH antagonist protocol

102 (18.8)

1153 (18.5)

405 (16.3)

 

 GnRH agonist long protocol

202 (37.1)

3183 (51.1)

1519 (61.1)

 

 GnRH agonist short protocol

187 (34.4)

1580 (25.3)

444 (17.8)

 

 GnRH agonist super long protocol

37 (6.8)

275 (4.4)

112 (4.5)

 

 Other protocol

16 (2.9)

43 (0.7)

8 (0.3)

 

 EMT on HCG trigger day, (mm)abc

7.57 ± 0.71

10.52 ± 1.06

13.38 ± 1.11

< 0.001d

 Progesterone level on HCG trigger day (ng/mL) ac

0.77 ± 0.37

0.82 ± 0.35

0.80 ± 0.34

0.001e

 E2 level on HCG trigger day (pg/mL)

2856.69 ± 1442.43

2878.68 ± 1431.83

2952.69 ± 1455.60

NSe

Number of embryos transferred, n (%) ab

0.002f

 1

210 (38.6)

1952 (31.3)

782 (31.4)

 

 2

334 (61.4)

4282 (68.7)

1706 (68.6)

 

 Blastocyst transfer, n (%)

165 (30.3)

1603 (25.7)

632 (25.4)

0.05f

  1. Values are presented as mean ± standard deviation or n (%). ANOVA analysis of variance, BMI body mass index, EMT endometrial thickness, HCG human chorionic gonadotropin, E2 estradiol, NS not statistically significant
  2. aStatistically significant differences between EMT ≤8 and 8 < EMT ≤12 mm groups
  3. bStatistically significant differences between EMT ≤8 mm and EMT > 12 mm groups
  4. cStatistically significant differences between 8 < EMT ≤12 mm and EMT > 12 mm groups
  5. dWelch’s ANOVA
  6. eOne-way ANOVA
  7. fPearson chi-square test
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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