Table 2 Neonatal characteristics and long-term neurodevelopment outcomes of the 31 children born following exposure to GnRH-a
Clinical data | Children born following exposure to GnRH-a (n = 31) | Children born following IVF (n = 45) | Children born following spontaneous conception (n = 45) | P value |
|---|---|---|---|---|
Mode of delivery | ||||
 Caesarean section %b | 40.0 (12/30) | 64.44(29/45) | 37.78(17/45) | 0.023 |
Neonatal health outcomes | ||||
 Gestational weeks | 37.97 ± 1.89 | 37.80 ± 2.37 | 38.60 ± 1.84 | 0.093 |
 Singleton birth | 29 | 33 | 45 | – |
 Twins | 1 | 6 | 0 | – |
 Birth weight (g) | 3175.81 ± 477.82 | 3160.00 ± 405.45 | 3308.89 ± 373.15 | 0.111 |
 Body height (cm) | 50.16 ± 2.53 | 49.73 ± 1.79 | 50.11 ± 1.19 | 0.449 |
 Apgar score | 9.97 ± 0.18 | 9.87 ± 0.34 | 9.93 ± 0.25 | 0.239 |
 Birth defects | 1 (Cleft lip) | 1 (ASD) | 0 | – |
Neurodevelopmental outcomes | ||||
 Children age (year) | 5.03 ± 1.80 | 5.22 ± 1.99 | 5.16 ± 1.15 | 0.860 |
 FSIQa | 105.77 ± 8.58 | 105.98 ± 10.61 | 104.60 ± 11.26 | 0.865 |
 ADHD | 0 | 2 | 1 | – |
 ASDs | 1 | 0 | 0 | – |