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Table 1 Clinical characteristics of the couples inadvertently exposed to GnRH-a soon after conception

From: No significant long-term complications from inadvertent exposure to gonadotropin-releasing hormone agonist during early pregnancy in mothers and offspring: a retrospective analysis

Clinical parameters

Couples with unexpected pregnancies associated with GnRH-a (n = 114)

P value

Women with live birth (n = 65)

Women without live birth (n = 49)

Female general characteristics

 Age (y)

29.02 ± 3.42

30.06 ± 3.82

0.127

 Duration of infertility (y)

3.13 ± 1.90

3.00 ± 2.49

0.749

 Primary infertility cases (%)

30 (46.15)

26 (53.06)

0.465

 BMI (kg/m2)

21.97 ± 3.20

21.04 ± 2.38

0.090

Basal serum sex hormone levels

 FSH (pmol/L)

6.94 ± 2.11

7.08 ± 1.75

0.711

 LH (pmol/L)

5.30 ± 3.15

4.84 ± 2.26

0.726

 E2 (pmol/L)

165.71 ± 133.16

173.99 ± 112.68

0.171

 T (pmol/L)

1.41 ± 1.34

1.19 ± 0.46

0.380

 PRL (pmol/L)

16.18 ± 11.53

19.31 ± 12.58

0.260

Number of antral follicles

 Right ovary

5.80 ± 2.29

5.33 ± 2.57

0.320

 Left ovary

5.46 ± 2.46

5.78 ± 2.31

0.490

Male characteristics

 Age (y)

30.85 ± 4.68

31.69 ± 4.21

0.320

 Sperm volume (ml)

3.52 ± 1.57

3.70 ± 1.59

0.542

 Sperm concentration (106/ml)

91.17 ± 81.43

70.15 ± 50.38

0.115

 Progress motility (%)

44.43 ± 17.57

42.34 ± 15.08

0.247

 Sperm abnormality rate (%)

90.33 ± 43.40

90.78 ± 43.85

0.433

  1. Annotation: BMI Body mass index, FSH Follicle stimulating hormone, LH Luteinizing hormone, E2 Estradiol, T Testosterone, PRL Prolactin