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Table 2 Clinical outcomes of patients following CsA vs. conventional treatment

From: Impacts of Cyclosporin A on clinical pregnancy outcomes of patients with a history of unexplained transfer failure: a retrospective cohort study

Outcome CsA Con Unadjusted
OR (95 % CI)
Rough Adjusted
OR (95 % CI)
Fine Adjusted
OR (95 % CI)
Implantation ratea (%) 46.7 (50/107) 39.2 (83/212) 1.363 (0.853–2.180) 1.134(0.678–1.898) 1.251 (0.739–2.120)
Biochemical pregnancya (%) 5.2 (3/58) 5.8 (7/120) 0.881 (0.219–3.536) 1.176 (0.264–5.232) 1.402 (0.285–6.909)
Clinical pregnancya (%) 63.8 (37/58) 47.5 (57/120) 2.194 (1.140–4.224) 1.574 (0.762–3.249) 1.634 (0.772–3.458)
Take-home baby ratea (%) 44.8 (26/58) 38.3 (46/120) 1.307 (0.693–2.466) 0.848 (0.416–1.728) 0.872 (0.423–1.798)
Singleton ratea (%) 80.8 (21/26) 71.7 (33/46) 1.00 1.00 1.00
Multiple births ratea (%) 19.2 (5/26) 28.3 (13/46) 0.604 (0.188–1.943) 0.795 (0.218–2.901) 0.840 (0.197–3.590)
Gestation at birth (wk)a (%)
 Normal, 37+ 73.1 (19/26) 80.4 (37/46) 1.00 1.00 1.00
 Preterm, < 37 19.2 (5/26) 19.6 (9/46) 1.082 (0.318–3.684) 1.355 (0.357–5.144) 1.668 (0.377–7.373)
Birth weight (kg)a (%)
 Normal weight, 2.5-4.0 72.4 (21/29) 74.6 (44/59) 1.00 1.00 1.00
 Abnormal weight 27.6 (8/29) 25.4 (15/59) 1.117 (0.410–3.047) 1.195 (0.408–3.499) 1.834 (0.533–6.307)
 Very low birth weight, < 1.5 6.9 (2/29) 0 (0/59)    
 Low birth weight, < 2.5 13.8 (4/29) 18.6 (11/59)    
 High birth weight, 4.0+ 6.9 (2/29) 6.8 (4/59)    
Sex of babya (%)
 Female 41.4 (12/29) 45.8 (27/59) 1.00 1.00 1.00
 Male 58.6 (17/29) 54.2 (32/59) 1.195 (0.486–2.937) 0.834 (0.311–2.235) 0.956 (0.339–2.698)
 Birth defects (%) 0 (0/29) 0 (0/59) - - -
  1. Values are shown as n (%). a Rough Adjusted for age and BMI. a Fine Adjusted for age, BMI, number of ET cycles, number of ET embryos, endometrium thickness and embryo stage.The reference variable within each sub-category has been arbitrarily designated and given the odds ratio of 1