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Table 2 Clinical outcomes of patients following CsA vs. conventional treatment

From: Impacts of Cyclosporin A on clinical pregnancy outcomes of patients with a history of unexplained transfer failure: a retrospective cohort study

Outcome

CsA

Con

Unadjusted

OR (95 % CI)

Rough Adjusted

OR (95 % CI)

Fine Adjusted

OR (95 % CI)

Implantation ratea (%)

46.7 (50/107)

39.2 (83/212)

1.363 (0.853–2.180)

1.134(0.678–1.898)

1.251 (0.739–2.120)

Biochemical pregnancya (%)

5.2 (3/58)

5.8 (7/120)

0.881 (0.219–3.536)

1.176 (0.264–5.232)

1.402 (0.285–6.909)

Clinical pregnancya (%)

63.8 (37/58)

47.5 (57/120)

2.194 (1.140–4.224)

1.574 (0.762–3.249)

1.634 (0.772–3.458)

Take-home baby ratea (%)

44.8 (26/58)

38.3 (46/120)

1.307 (0.693–2.466)

0.848 (0.416–1.728)

0.872 (0.423–1.798)

Singleton ratea (%)

80.8 (21/26)

71.7 (33/46)

1.00

1.00

1.00

Multiple births ratea (%)

19.2 (5/26)

28.3 (13/46)

0.604 (0.188–1.943)

0.795 (0.218–2.901)

0.840 (0.197–3.590)

Gestation at birth (wk)a (%)

 Normal, 37+

73.1 (19/26)

80.4 (37/46)

1.00

1.00

1.00

 Preterm, < 37

19.2 (5/26)

19.6 (9/46)

1.082 (0.318–3.684)

1.355 (0.357–5.144)

1.668 (0.377–7.373)

Birth weight (kg)a (%)

 Normal weight, 2.5-4.0

72.4 (21/29)

74.6 (44/59)

1.00

1.00

1.00

 Abnormal weight

27.6 (8/29)

25.4 (15/59)

1.117 (0.410–3.047)

1.195 (0.408–3.499)

1.834 (0.533–6.307)

 Very low birth weight, < 1.5

6.9 (2/29)

0 (0/59)

   

 Low birth weight, < 2.5

13.8 (4/29)

18.6 (11/59)

   

 High birth weight, 4.0+

6.9 (2/29)

6.8 (4/59)

   

Sex of babya (%)

 Female

41.4 (12/29)

45.8 (27/59)

1.00

1.00

1.00

 Male

58.6 (17/29)

54.2 (32/59)

1.195 (0.486–2.937)

0.834 (0.311–2.235)

0.956 (0.339–2.698)

 Birth defects (%)

0 (0/29)

0 (0/59)

-

-

-

  1. Values are shown as n (%). a Rough Adjusted for age and BMI. a Fine Adjusted for age, BMI, number of ET cycles, number of ET embryos, endometrium thickness and embryo stage.The reference variable within each sub-category has been arbitrarily designated and given the odds ratio of 1