Table 1 Effect of 17-AAG on motility parameters in human sperm
From: Hsp90 modulates human sperm capacitation via the Erk1/2 and p38 MAPK signaling pathways
|  | DMSO | 5 µM 17-AAG |
|---|---|---|
Motility (%) | 62.5 ± 8.5 | 51.4 ± 2.9 |
VSL (µm/s) | 53.5 ± 4.0 | 48.6 ± 1.8 |
VCL (µm/s) | 111.3 ± 4.5 | 93.5 ± 2.4 |
VAP (µm/s) | 64.7 ± 3.7 | 57.3 ± 1.9 |
STR (%) | 80.8 ± 1.8* | 82.2 ± 0.5* |
LIN (%) | 48.5 ± 1.9 | 52.0 ± 0.8 |
ALH (µm) | 4.7 ± 0.2 | 4.1 ± 0.1 |
BCF (Hz) | 28.9 ± 1.2 | 28.9 ± 0.4 |
Progressive sperm (%) | 39.8 ± 5.8* | 33.4 ± 2.6* |
Hyperactivation (%) | 10.5 ± 1.5* | 3.4 ± 0.5* |