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Fig. 5 | Reproductive Biology and Endocrinology

Fig. 5

From: Hsp90 modulates human sperm capacitation via the Erk1/2 and p38 MAPK signaling pathways

Fig. 5

Interaction between Hsp90 and p38 during human sperm capacitation. a. Hsp90 was detected in sperm lysates using western blotting and Co-IP with non-immune rabbit IgG or antibodies against p38. No interaction was observed between non-immune rabbit IgG and Hsp90, whereas there was a clear interaction between Hsp90 and p38 that was significantly disrupted by 17-AAG. b. The interaction between Hsp90 and p38 with or without 5 µM 17-AAG during human sperm capacitation

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