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Table 1 Embryotoxic and morphometric analysis of pregnancy outcome in the four different groups

From: Effect of edaravone on pregnant mice and their developing fetuses subjected to placental ischemia

 

SV

n = 62

SE

n = 55

RV

n = 57

RE

n = 65

Mean number of fetuses at surgery (GD13)

8 ± 1

7 ± 1

7 ± 1

8 ± 1

Mean number of fetuses at sacrifice (GD18)

7 ± 1

6 ± 1

4 ± 1

6 ± 1

Fetal Loss

(2) 3.23%

(3) 5.45%

(26) 45.61%

(16) 24.62%

Fetal absorption

(2) 100%

(2) 66.67%

(18) 69.23%

(11) 68.75%

Fetal death

0%

(1) 33.33%

(8) 30.77%

(5) 31.25%

Fetal viability

96.77%

94.55%

54.39%

75.38%

Mean fetal crown-rump length (cm)

2.16 ± 0.081

2.03 ± 0.121

1.52 ± 0.089**

1.85 ± 0.151#

Mean fetal weight (g)

0.952 ± 0.017

0.888 ± 0.023

0.403 ± 0.025**

0.687 ± 0.017*#

Mean placental weight (g)

0.121 ± 0.004

0.117 ± 0.001

0.071 ± 0.003**

0. 096 ± 0.002*#

Mean fetal weight: placental weight

7.87

7.59

5.68

7.15

  1. Data are represented as mean ± SD
  2. * p < 0.05 ** p < 0.01 compared with the SV group
  3. # p < 0.05 compared with RV group