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Table 7 Docking results of standard drugs on overexpressed proteins

From: Identification of key pathways and genes in polycystic ovary syndrome via integrated bioinformatics analysis and prediction of small therapeutic molecules

Sl. No/ Code

Over expressed gene: POLR2K

Over expressed gene: RPS15

Over expressed gene: RPS15 alpha

Over expressed gene: SAA1

PDB: 1LE9

PDB: 3OW2

PDB: 1G1X

PDB: 4IP8

Total Score

Crash

(-Ve)

Polar

Total Score

Crash

(-Ve)

Polar

Total Score

Crash

(-Ve)

Polar

Total Score

Crash

(-Ve)

Polar

ETE

8.019

-0.755

1.219

8.223

-1.768

2.517

8.260

-0.857

3.135

9.943

-1.689

0.891

LNG

7.973

-0.945

1.295

8.351

-2.752

3.465

7.854

-0.599

2.373

8.535

-1.948

0.057

DSG

8.273

-1.124

1.116

5.674

-1.611

2.212

7.745

-1.046

2.306

8.158

-1.997

0.000