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Fig. 6 | Reproductive Biology and Endocrinology

Fig. 6

From: Irisin deletion induces a decrease in growth and fertility in mice

Fig. 6

Effects of irisin on hormone production in KGN cells. Cells were incubated with increasing concentrations of irisin (10–30 nM) or si-Fndc5 (100 nM). a: Irisin stimulated the phosphorylation of the p38 and ERK proteins. b: The E2 concentration in the conditioned culture medium was measured by a specific radioimmunoassay. c: The progesterone (P) concentration was measured. Data are presented as the mean ± SD, (n = 3 per group); *P < 0.05 compared to the control group

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