Fig. 1From: Irisin deletion induces a decrease in growth and fertility in mice[30] Generation of Fndc5 mutation mice. a: Schematic representation of the gene targeting procedure. The black arrowhead indicates the target exon. b: Sequences of the Fndc5 mRNA transcripts in mice and the proteins predicted to be encoded by the respective mRNAs. c: Confirmation of Fndc5 mutation. Genotyping (left panel) and Western blot (right panel) analyses were consistent with successful Fndc5 mutationBack to article page