Fig. 5
Effects of a CB1 receptor antagonist and agonist on the proliferation of JZSMCs. a JZSMCs were treated with the CB1 receptor antagonist AM251 at different concentrations, and the cell survival rates were analysed. b Inhibition effect of AM251 at different concentrations on adenomyotic JZSMCs. The X axis corresponds to the 50% inhibition rate (the logarithm (base ten) of the half maximal inhibitory concentration (IC50)). c The cell survival rates after incubation with the CB1 receptor agonist ACEA at different concentrations are shown. d Comparison of the cell survival rates after incubation with different drugs. Three independent experiments were conducted for each treatment. One representative image from each group of three experiments is shown (Log10 M is the logarithm of the molar concentration to 10, * P < 0.05; ** P < 0.01, ***, P < 0.001, ****, P < 0.0001)