Table 1 Demographic and clinical characteristics of the participants

Age (years), mean ± SD

27.44 ± 4.21

27.02 ± 4.76

0.363

Height (m), mean ± SD

1.60 ± 0.03

1.60 ± 0.04

0.994

Body mass index (Kg/m²), mean ± SD

20.31 ± 2.03

20.72 ± 3.01

0.131

Overweight or Obesity, n (%)

17 (5.7%)

17 (11.3%)

0.032

Smoking, n (%)

7 (2.3%)

5 (3.3%)

0.756

Drink, n (%)

6 (2.0%)

4 (2.7%)

0.910

Hypertensive family history, n (%)

13 (4.3%)

8 (5.3%)

0.635

Estradiol (pmol/L), median (IQR)

171.00 (135.5–218.75)

141.50 (98.75–206.25)

0.856

Prolactin (ug/L), median (IQR)

15.04 (8.52–20.58)

15.84 (10.99–25.18)

0.385

Testosterone (ug/L), median (IQR)

0.49 (0.42–0.53)

0.54 (0.44–0.68)

0.315

Follicle-stimulating hormone (IU/L, median (IQR)

8.05 (6.45–13.55)

7.05 (5.95–7.93)

0.102

Luteinizing hormone (IU/L), median (IQR)

4.54 (3.75–9.96)

5.67 (4.05–7.66)

0.554

Cholesterol (mmol/L), median (IQR)

4.66 (3.77–5.02)

4.37 (3.87–4.79)

0.157

Triglyceride (mmol/L), median (IQR)

0.84 (0.63–1.41)

0.82 (0.64–1.13)

0.561

Fasting glucose (mg/dl), median (IQR)

4.73 (4.62–5.22)

4.99 (4.81–5.24)

0.116

Fasting insulin (µU/ml), median (IQR)

5.76 (3.71–8.07)

5.24 (3.62–8.19)

0.514

Folate (ng/mL), mean ± SD

11.99 ± 2.58

10.49 ± 3.83

< 0.001

Homocysteine (µmol/L), mean ± SD

8.13 ± 1.21

10.07 ± 2.06

< 0.001