Fig. 5
From: Genipin improves reproductive health problems caused by circadian disruption in male mice
Genipin upregulates steroidogenesis in mouse ledig tumor MLTC-1 cells. a GNP increased progesterone secreted in MLTC-1. b Protein levels of StAR and CYP11A1 were upregulated by GNP in MLTC-1. c The statistical quantification of panel b. d mRNA levels of StAR and CYP11A1,in MLTC-1 after treated with or without GNP. **P < 0.01; ***P < 0.001. e The model of circadian disruption of spermatogenesis and fertility in male mice and its improvement by genipin