Skip to main content
Fig. 1 | Reproductive Biology and Endocrinology

Fig. 1

From: Growth hormone activates PI3K/Akt signaling and inhibits ROS accumulation and apoptosis in granulosa cells of patients with polycystic ovary syndrome

Fig. 1

GH inhibits ROS accumulation in GCs of patients with PCOS. a Visualized by fluorescent microscopy, the green fluorescence intensity of ROS in GCs of the PCOS-GH group was weaker compare to that in the PCOS-C group, but similar to that of non-PCOS controls. The blue fluorescence signal indicates cell nucleus stained by DAPI. Scale bars: 20 μm. b Quantitative detection by using a spectrophotometer. The fluorescence intensity of ROS was expressed as the fold change relative to the control. ROS intensity was significantly lower in the PCOS-GH group than in the PCOS-C group (1.10 ± 0.21 vs. 2.78 ± 0.35) (P < 0.05), but no difference with non-PCOS controls (1.00 ± 0.21) (P > 0.05). *P < 0.05 compared with the PCOS-C group

Back to article page