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Table 2 Results of meta-analysis before and after sensitivity analysis

From: Thyroid autoimmunity and IVF/ICSI outcomes in euthyroid women: a systematic review and meta-analysis

Outcome Unadjusted OR / SMD (95% CI) P value I2 Studies Excluded Following Sensitivity Analysis OR (95% CI) Following Exclusion of Studies due to Sensitivity Analysis P value I2
CPR - overall OR 0.86; 95%CI [0.70, 1.05] 0.14 29%     
CPR - euthyroid OR 0.88; 95%CI [0.69, 1.12]; 0.29 32%     
CMR – overall OR 1.04; 95%CI [0.52, 2.07] 0.908 53% Poppe 2003 OR 0.74; 95%CI [0.46, 1.19) 0.21 0.00%
CMR – euthyroid OR 1.18; 95%CI [0.52, 2.64] 0.69 54% Poppe 2003 OR 0.81; 95%CI [0.46, 1.41] 0.45 0.00%
BPL- overall OR 1.14; 95%CI [0.48, 2.72] 0.769 0%     
BPL- euthyroid -       
MR - overall OR 1.33; 95%CI [0.83, 2.15] 0.23 47%     
MR - euthyroid OR 1.26; 95%CI [0.72–2.18] 0.42 35%     
LBR/CP - overall OR 0.67; 95%CI [0.28, 1.60] 0.37 69% Poppe 2003 OR 0.92; 95%CI [0.57, 1.48] 0.722 0.00%
LBR/CP - euthyroid       
LBR/cycle - overall OR 0.84; 95%CI [0.67, 1.06] 0.15 2%     
LBR/cycle – euthyroid -       
ET - overall SMD 0.02; 95%CI [−0.18, 0.22] 0.85 69% Chen 2017 SMD 0.13; 95%CI [−0.00, 0.26] 0.054 0.00%
ET - euthyroid SMD 0.07; 95%CI [− 0.13, 0.2] 0.49 0%     
NOR – overall SMD −0.07; 95%CI [− 0.20, 0.06] 0.27 49%     
NOR - euthyroid SMD −0.05; 95%CI [− 0.25, 0.16] 0.67 60% Karacan 2013 SMD −0.14; 95%CI [− 0.30, 0.02] 0.08 26%
Age - overall SMD 0.12; 95%CI [−0.04, 0.28] 0.15 76%     
Age - euthyroid SMD 0.13; 95%CI [−0.10, 0.36] 0.25 82%     
TSH - overall SMD 0.28; 95%CI [−0.03, 0.59] 0.08 79%     
TSH – euthyroid SMD 0.14; 95%CI [−0.07, 0.34] 0.19 46%     
  1. CPR, clinical pregnancy rate; CMR, clinical miscarriage rate; BPL, biochemical pregnancy loss; MR; miscarriage rate according to all definitions; LBR/CP, live birth rate per clinical pregnancy; LBR/ cycle, live birth rate per cycle; IR, implantation rate; ET, mean number of embryos transferred; NOR, number of oocytes retrieved