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Table 1 Characteristics of the included studies that examined associations of PON single nucleotide variants with PCOS

From: Paraoxonase single nucleotide variants show associations with polycystic ovary syndrome: a meta-analysis

  Included in previous meta-analyses First author [R] Year Country Ethnicity Diagnostic criteria PON1 variants Clark-Baudouin score
Liu [21] Liao [20] Gu [19] Chen [18]
1 yes yes no yes San Millan [40] 2004 Spain Caucasian National Institute of Health rs85460, rs662, rs705379 8
2 no yes no no Mohammed [41] 2009 Egypt African National Institute of Health rs854560a, rs705379 5
3 yes yes yes yes Lenarcik [42] 2010 Poland Caucasian Rotterdam rs854560 6
4 yes yes no no Zhang (Ch) [43] 2011 China Asian Rotterdam rs705379 6
5 yes yes yes yes Wang [38] 2012 China Asian Rotterdam rs854560, rs662 7
6 yes yes yes yes Paltoglu [44] 2013 Greece Caucasian National Institute of Health rs662, rs705379 8
7 yes yes yes yes Ferk [45] 2014 Slovenia Caucasian Rotterdam rs705379 6
8 yes yes yes yes Dadachanji [46] 2015 India Asian Rotterdam rs854560, rs662 8
9 yes yes yes yes Zhang [39] 2015 China Asian Rotterdam rs854560, rs662, rs705379 7
10 no no no no Dadachanji [47] 2018 India Asian Rotterdam rs705379, rs854571, rs854572, rs854573, rs705381 8
11 no no no no Liu [48] 2019 China Asian Rotterdam rs7493 (PON2) 9
12 no no no no Nalkiran [49] 2019 Turkey Caucasian Rotterdam rs854560, rs662a 8
  1. PON Paraoxonase, PCOS polycystic ovary syndrome, (Ch) Chinese language, [R] reference number
  2. acontrol frequencies deviated from the Hardy-Weinberg Equilibrium