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Fig. 5 | Reproductive Biology and Endocrinology

Fig. 5

From: Paraoxonase single nucleotide variants show associations with polycystic ovary syndrome: a meta-analysis

Fig. 5

Post-outlier association of PON LD1 with PCOS, the overall het analysis. The diamond shows the pooled effect indicating decreased risk (OR 0.85), which was significant (Pa = 0.008) and homogeneous (PHET = 0.60, I2 = 0%). Squares indicate the OR in each study, with square sizes directly proportional to the weight contribution (%) of the study. Horizontal lines on either side of the squares represent 95% CIs. PON: paraoxonase; LD1: linkage disequilibrium 1; PCOS: polycystic ovary syndrome; het: heterozygous genotype (var + wt); OR: identifier after author name indicate 0 (rs854560) or 2 (rs662); odds ratio; Pa: P-value for association; PHET: P-value for heterogeneity; I2: measure of variability; CIs: confidence intervals

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