Fig. 3

Pre-outlier association of PON LD1 with PCOS, the overall het analysis. The diamond indicates a pooled null effect (OR 1.00), not significant (P^a = 0.97) and heterogeneous (P_HET < 0.0001, I² = 74%). Squares indicate the OR in each study, with square sizes directly proportional to the weight contribution (%) of the study. Horizontal lines on either side of the squares represent 95% CIs. PON: paraoxonase; LD1: linkage disequilibrium 1; PCOS: polycystic ovary syndrome; het: heterozygous genotype (var + wt); identifier after author name indicate 0 (rs854560) or 2 (rs662); OR: odds ratio; P^a: P-value for association; P_HET: P-value for heterogeneity; I²: measure of variability; CIs: confidence intervals