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Table 1 Baseline characteristics, treatment, and outcomes for fresh, nondonor cycles among black and white women

From: Status of racial disparities between black and white women undergoing assisted reproductive technology in the US

 

No Prior ART

Prior ART

Black (n = 8458)

White (n = 64,878)

 

Black (n = 5259)

White (n = 44,126)

 

Characteristics (% reporting)

% (95% CI)

% (95% CI)

p

% (95% CI)

% (95% CI)

p

Women’s age (year)

  

< 0.001

  

< 0.001

  < 35

38.5 (37.5–39.6)

54.6 (54.2–55)

 

20.9 (19.8–22.1)

32.2 (32.2–33.1)

 

 35–37

22.4 (21.5–23.3)

21.2 (20.8–21.5)

 

17.7 (16.6–18.7)

21.9 (21.5–22.3)

 

 38–40

19.8 (18.9–20.6)

15.2 (14.9–15.4)

 

24.7 (23.6–25.9)

22.1 (21.7–22.4)

 

 41–42

10.1 (9.4–10.7)

5.7 (5.5–5.8)

 

16.3 (15.3–17.3)

11.8 (11.5–12.1)

 

  > 42

9.3 (8.7–9.9)

3.5 (3.3–3.6)

 

20.4 (19.3–21.5)

11.7 (11.4–12)

 

BMI > =30

47.4 (46.4–48.5)

31.5 (31.1–31.9)

<.001

49.4 (48–50.7)

34.5 (34.1–35)

< 0.001

Nulliparous

55.6 (54.1–57.1)

51.2 (50.5–51.8)

< 0.001

53.3 (51.7–55)

44.4 (43.8–44.9)

< 0.001

Past spontaneous abortions

28.6 (27.6–29.6)

20.2 (19.9–20.5)

< 0.001

41.1 (39.8–42.5)

32.8 (32.4–33.3)

< 0.001

Diagnosis

 Tubal Factor

29.8 (28.8–30.8)

11 (10.8–11.2)

< 0.001

29.1 (27.8–30.3)

10.4 (10.2–10.7)

< 0.001

  Tubal Ligation

3.2 (2.8–3.6)

1.7 (1.6–1.8)

< 0.001

2.1 (1.7–2.5)

1 (0.9–1.1)

< 0.001

  Hydrosalpinx

2.9 (2.6–3.3)

0.8 (0.7–0.8)

< 0.001

2.9 (2.5–3.4)

0.7 (0.6–0.8)

< 0.001

  Other

24.2 (23.3–25.2)

8.6 (8.4–8.9)

< 0.001

24.5 (23.4–25.7)

8.8 (8.6–9.2)

< 0.001

Male Infertility

31.6 (30.6–32.6)

34.2 (33.9–34.6)

< 0.001

31.3 (30.1–32.6)

36 (35.5–36.4)

< 0.001

Uterine Factor

12.6 (11.9–13.4)

3.8 (3.6–3.9)

< 0.001

14.5 (13.6–15.5)

4.5 (4.3–4.7)

< 0.001

History of endometriosis

6 (5.5–6.5)

9.2 (9–9.4)

< 0.001

7.4 (6.7–8.1)

9.8 (9.5–10.1)

< 0.001

Diminished ovarian reserve

27.4 (26.4–28.3)

21.5 (21.2–21.8)

< 0.001

44.9 (43.5–46.2)

41.3 (40.8–41.7)

0.73

Unexplained

7.3 (6.7–7.9)

13.3 (13–13.6)

< 0.001

5.7 (5.1–6.4)

10.4 (10.1–10.7)

< 0.001

Ovulation Disorder (PCOS)

9 (8.4–9.6)

13.9 (13.7–14.2)

< 0.001

6.8 (6.1–7.5)

10.2 (10–10.5)

< 0.001

Other

22.5 (21.6–23.4)

25.5 (25.1–25.8)

< 0.001

20.4 (19.3–21.5)

21.2 (20.9–21.6)

0.15

Metrics of ovarian reserve

 Day 3 FSH > =10 (IU/L)

71.8 (70.8–72.8)

65.4 (65.1–65.8)

< 0.001

81.2 (80.1–82.2)

74 (73.6–74.4)

< 0.001

 Mean Day 3 FSH (IU/L)

11.5 (11.2–11.83)

11.7 (11.65–11.75)

0.217

11.6 (11.55–11.65)

12.0 (11.7–12.2)

0.024

 FSH dosage > = 37 ampules (91.7)

59 (57.9–60.1)

52.2 (51.8–52.6)

< 0.001

69 (67.7–70.4)

64.8 (64.3–65.2)

< 0.001

 Mean AMH (ng/mL)

3.2 (3.1–3.3)

3.4 (3.4–3.4)

0.003

2.1 (2.0–2.2)

2.3(2.3–2.3)

< 0.001

 AMH < 1 among women< 40 yr

13.4 (12.6–14.3)

13.4 (13.1–13.6)

0.95

21.7 (20.2–23.3)

21 (20.6–21.5)

0.4

High ovarian response

0.8 (0.7–10.6)

0.5 (0.4–0.5)

< 0.001

1 (0.8–1.3)

0.7 (0.7–0.8)

0.049

Mean oocytes retrieved

13.8 (13.6–14.0)

14.3 (14.2–14.4)

< 0.001

14.4 (14.1–14.7)

14.5 (14.4–14.6)

0.52

Mean embryos cryopreserved

2.70 (2.61–2.79)

2.75 (2.72–2.78)

0.24

1.29 (1.22–1.36)

1.30 (1.28–1.32)

0.77

Cycle Cancelled

12.9 (12.2–13.6)

9.9 (9.6–10.1)

< 0.001

17.1 (16.1–18.1)

13.3 (13.0–13.6)

< 0.001

 Due to low response

76.4 (73.8–78.9)

84.1 (83.2–85)

< 0.001

77 (74.1–79.7)

80.1 (79.1–81.1)

0.03

ICSI

57.7 (56.7–58.8)

61.2 (60.8–61.6)

< 0.001

58.3 (56.9–59.6)

63.9 (63.4–64.3)

< 0.001

No of embryos

  

< 0.001

  

0.018

 1

34.9 (33.6–36.3)

38.2 (37.7–38.6)

 

25.6 (24–27.3)

26.3 (25.8–26.8)

 

 2

53.4 (52–54.8)

54.1 (53.6–54.6)

 

51.5 (49.7–53.4)

53.1 (52.5–53.7)

 

 3+

11.7 (10.8–12.6)

7.7 (7.5–8)

 

22.8 (21.3–24.4)

20.6 (20.1–21.1)

 

No. of embryos transferred: mean (sd)

1.8 (0.74)

1.7 (0.67)

< 0.001

2.06 (0.9)

2.02 (0.88)

0.03

Implantation rate %: mean (sd)

72.4 (32.4)

76.5 (33.4)

< 0.001

63.9 (35.3)

67.1 (34.1)

0.01

Treatment outcome

 Clinical intrauterine gestation (CIG)

24.4 (23.5–25.3)

33 (32.7–33.4)

<.001

17.2 (16.2–18.2)

25.1 (24.7–25.3)

< 0.001

  Spontaneous abortion

21 (19.3–22.8)

14.5 (14–15)

0.2

27.5 (24.6–30.5)

18.6 (17.8–19.3)

<.001

  Live birth per CIG

76.4 (74.5–78.2)

84.6 (84.1–85)

<.001

69.8 (66.6–72.7)

80.5 (79.7–81.2)

< 0.001

 Biochemical pregnancy

4.8 (4.4–5.3)

5.7 (5.5–5.9)

0.0013

4.2 (3.7–4.8)

5.7 (5.5–6)

< 0.001

 Ectopic or heterotopic

0.5 (0.4–0.7)

0.5 (0.5–0.6)

0.75

0.3 (0.1–0.5)

0.5 (0.4–0.6)

0.02

 Not pregnant

58.3 (57.2–59.4)

47.2 (46.8–47.6)

<.001

68.4 (67.1–70)

58.3 (57.8–58.7)

< 0.001

Live birth per cycle started

18.6 (17.8–19.5)

27.9 (27.6–28.3)

<.001

12 (11.1–12.9)

20.2 (19.8–20.6)

< 0.001

Plurality of birth (24)

  

<.001

  

< 0.001

 Singleton

76 (73.8–78)

76.9 (76.2–77.5)

 

75.2 (71.7–78.5)

75.8 (74.9–76.6)

 

 Twins

21.2 (19.2–23.3)

21.9 (21.3–22.5)

 

21.1 (18–24.5)

22.6 (21.8–23.5)

 

 Triples or more

2.8 (2.1–3.8)

1.3 (1.1–1.5)

 

3.7 (2.4–5.5)

1.6 (1.3–1.9)

 

eSET (%) < 38 y/o (44.1)

21 (19.9–22.2)

23.9 (31.5–31.9)

<.001

12.7 (11.3–14.2)

13.9 (13.4–14.3)

0.16

States

 Mandated

34.7 (33.7–35.7)

27.7 (27.4–28.1)

<.001

39.8 (38.4–41.1)

32.4 (32–32.9)

<.001

 Non-mandated

65.1 (64.1–66.1)

71.5 (71.1–71.8)

<.001

60.2 (58.9–61.5)

67 (66.5–67.4)

<.001