Fig. 4From: Cyclosporin A protects JEG-3 cells against oxidative stress-induced apoptosis by inhibiting the p53 and JNK/p38 signaling pathwaysEffects of CsA on H2O2-induced expression of pro-caspase-3 and cleaved PARP in JEG-3 cells. a JEG-3 cells were pretreated with 1 μM CsA for 24 h followed by treatment with 500 μM H2O2 for another 24 h. Total cell lysates were harvested for the western blot analysis of pro-caspase-3 and cleaved PARP expression. GAPDH was used as a loading control. b Quantitative analysis of pro-caspase-3 and cleaved PARP expression levels. The data presented are representative of three independent experiments. *p < 0.05, compared to the control; # p < 0.05, compared to the H2O2-treated groupBack to article page