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Fig. 3 | Reproductive Biology and Endocrinology

Fig. 3

From: Cyclosporin A protects JEG-3 cells against oxidative stress-induced apoptosis by inhibiting the p53 and JNK/p38 signaling pathways

Fig. 3

Effects of CsA on H2O2-induced expression of p-p53, p53, Bax and Bcl-2 in JEG-3 cells. a JEG-3 cells were pretreated with 1 μM CsA for 24 h followed by treatment with 500 μM H2O2 for another 24 h. Total cell lysates were harvested for western blot analysis of p-p53, p53, Bax and Bcl-2 expression. GAPDH was used as a loading control. b Quantitative analysis of p-p53 and p53 expression levels. c Quantitative analysis of Bax expression levels. d Quantitative analysis of Bcl-2 expression levels. The data presented are representative of three independent experiments. *p < 0.05, compared to the control; # p < 0.05, compared to the H2O2-treated group

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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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