Fig. 1From: Cyclosporin A protects JEG-3 cells against oxidative stress-induced apoptosis by inhibiting the p53 and JNK/p38 signaling pathwaysCsA protects JEG-3 cells against H2O2–induced cytotoxicity. a JEG-3 cells were pretreated with 1 μM CsA for 24 h followed by treatment with 500 μM H2O2 for another 24 h. Cell viability was measured by MTT assay. Error bars depict the SEM. *p < 0.05, compared to the control; # p < 0.05, compared to the H2O2-treated group. b As observed with DAPI staining with a fluorescence microscope (original magnification 200×), the H2O2-treated cells exhibited nuclear condensation and fragmentation. The data presented are representative of three independent experimentsBack to article page