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Table 5 Comparison of outcomes at LPS stage of different trigger medicine at LPS stage of DuoStim protocol

From: The best execution of the DuoStim strategy (double stimulation in the follicular and luteal phase of the same ovarian cycle) in patients who are poor ovarian responders

Characteristic uhCG rhCG GnRha P value
Number 196 93 15  
AFC 4.89 ± 3.89 5.62 ± 4.89 4.87 ± 3.44 0.385
FSH (IU/L) 10.14 ± 4.93 10.18 ± 5.35 12.22 ± 7.06 0.321
Matemal age (years) 38.20 ± 4.83 38.10 ± 5.49 39.67 ± 5.70 0.531
Total dose of gonadotrophin (IU) 1633.29 ± 854.97 1791.68 ± 932.68 1570.00 ± 918.76 0.325
Duration of stimulation (days) 7.04 ± 2.94 7.47 ± 3.37 6.93 ± 3.81 0.527
follicle of >10 mm on HCG day 4.32 ± 4.07 5.38 ± 5.38 4.69 ± 3.17 0.176
No. of oocyte retrieved 3.39 ± 4.32 4.08 ± 5.17 2.93 ± 2.71 0.419
No. of fertilized oocytes 2.16 ± 2.79 2.48 ± 3.14 1.93 ± 1.58 0.614
No. of cleaved embryos 2.11 ± 2.74 2.45 ± 3.08 1.80 ± 1.42 0.531
No. of cryopreserved embryos 1.61 ± 2.38 2.27 ± 2.93 1.67 ± 1.35 0.118
No. of good embryos 1.43 ± 2.31 2.03 ± 2.68 1.67 ± 1.35 0.138
Fertilization rates (%) 63.16% 60.95% 65.91% 0.694
Cleaved embryos rates (%) 98.33% 98.70% 93.10% 0.095
Rate of cryopreserved embryos (%) 76.51% 92.54%* 92.59% 0
Rate of good embryos (%) 67.55% 82.89%* 92.59%* 0
Pregnancy rate per oocyte retrieval (%) 24.63% (33/134) 27.27%(18/66) 7.69%(1/13) 0.322
Pregnancy /FET (%) 47.76% (32/ 67) 54.20%(19/ 35) 12.5%(1 /8) 0.101
Implantation rate (%) 28.25% (50/177) 37.33%(28/75) 7.69%(1 / 13) 0.072
Spontaneous abortion rate (%) 18.75% (6 / 32) 21.05%(4/19) 100.00%(1/ 1) 0.147
  1. Data are presented as number (%) unless otherwise indicated. Independent t-test was used to compare continuous variables, and Chi-squared test or Fisher’s exact test for categorical ones
  2. *Compared with uHCG 10,000 IU Group, P < 0.05