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Table 5 Comparison of outcomes at LPS stage of different trigger medicine at LPS stage of DuoStim protocol

From: The best execution of the DuoStim strategy (double stimulation in the follicular and luteal phase of the same ovarian cycle) in patients who are poor ovarian responders

Characteristic

uhCG

rhCG

GnRha

P value

Number

196

93

15

 

AFC

4.89 ± 3.89

5.62 ± 4.89

4.87 ± 3.44

0.385

FSH (IU/L)

10.14 ± 4.93

10.18 ± 5.35

12.22 ± 7.06

0.321

Matemal age (years)

38.20 ± 4.83

38.10 ± 5.49

39.67 ± 5.70

0.531

Total dose of gonadotrophin (IU)

1633.29 ± 854.97

1791.68 ± 932.68

1570.00 ± 918.76

0.325

Duration of stimulation (days)

7.04 ± 2.94

7.47 ± 3.37

6.93 ± 3.81

0.527

follicle of >10 mm on HCG day

4.32 ± 4.07

5.38 ± 5.38

4.69 ± 3.17

0.176

No. of oocyte retrieved

3.39 ± 4.32

4.08 ± 5.17

2.93 ± 2.71

0.419

No. of fertilized oocytes

2.16 ± 2.79

2.48 ± 3.14

1.93 ± 1.58

0.614

No. of cleaved embryos

2.11 ± 2.74

2.45 ± 3.08

1.80 ± 1.42

0.531

No. of cryopreserved embryos

1.61 ± 2.38

2.27 ± 2.93

1.67 ± 1.35

0.118

No. of good embryos

1.43 ± 2.31

2.03 ± 2.68

1.67 ± 1.35

0.138

Fertilization rates (%)

63.16%

60.95%

65.91%

0.694

Cleaved embryos rates (%)

98.33%

98.70%

93.10%

0.095

Rate of cryopreserved embryos (%)

76.51%

92.54%*

92.59%

0

Rate of good embryos (%)

67.55%

82.89%*

92.59%*

0

Pregnancy rate per oocyte retrieval (%)

24.63% (33/134)

27.27%(18/66)

7.69%(1/13)

0.322

Pregnancy /FET (%)

47.76% (32/ 67)

54.20%(19/ 35)

12.5%(1 /8)

0.101

Implantation rate (%)

28.25% (50/177)

37.33%(28/75)

7.69%(1 / 13)

0.072

Spontaneous abortion rate (%)

18.75% (6 / 32)

21.05%(4/19)

100.00%(1/ 1)

0.147

  1. Data are presented as number (%) unless otherwise indicated. Independent t-test was used to compare continuous variables, and Chi-squared test or Fisher’s exact test for categorical ones
  2. *Compared with uHCG 10,000 IU Group, P < 0.05